The Government of Madrid (CAM) has recently granted a scientific project named CENTROSOME_CM (CAM - P2006/Gen-0166) that aims at studying the centrosome, a key cellular organelle in the organization process of the cellular architecture. In this project a multidisciplinary scientific research groups from Madrid are joining their expertise and efforts to provide a qualitative push to the current body of knowledge about the centrosome, fundamental to the understanding of the cell.
This project proposes a series of joint scientific activities by groups with expertise in Cellular Biology, Proteomics, Bioinformatics and Structural Biology, to gain relevant results in the area of Biomedicine. This novel workflow would involve Proteomics, in the analysis of sub-proteomes; Bioinformatics, for the management of complex data sets; and the three techniques available today for the structural characterization of proteins and its complexes: three-dimensional electron microscopy (and possibly of x-ray tomography), x-ray diffraction and nuclear magnetic resonance.
Our intention is to establish in the Community of Madrid (CAM) an authentic Integrated Functional Analysis Platform, with well defined procedures, that will permit the understanding of complex biological processes. This versatile Platform could, in the near future, nucleate other projects and other initiatives within the Science-Industry-Society framework in the CAM. The creation of the mentioned Platform is the main strategic goal, the workflow, however, must be developed working in specific biological systems.